Our Research:

Our laboratory studies the mechanisms of neural plasticity underlying sensorimotor learning and stroke recovery by applying innovative multimodal neuroimaging and electrophysiological techniques. We use both human and rodent models to examine translational questions at multiple levels, including behavioral, cellular, and circuits.

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Why:
We are particularly interested in understanding how the brain and spinal cord circuits interact and remodel to support learning in the intact nervous system and recovery after stroke. We use this knowledge to develop/optimize novel therapies based on neuromodulation for promoting motor recovery in stroke patients.

How:
Our lab uses a variety of multimodal techniques including simultaneous brain-spinal cord fMRI, paired-pulse electrical stimulation, and transcranial magnetic stimulation.
In rodents, we use optogenetic fMRI for cell-type specific stimulation and visualization of neural circuits.

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